In "Chainsaw," Chanel #5 angrily leaves Kappa Kappa Tau. She is frightened by The Red Devil's killing spree and angry at Chanel Oberlin for being apathetic. Chanel decides to replace Chanel #5 with Hester "Neckbrace" Ulrich. Chanel gives Hester an ultimate beauty makeover and enlists her as one of her loyal minions; Chanel #6.
KKT pledges Grace Gardner and Zayday Williams and the KKT security guard Denise Hemphill go upstairs to Chanel #2's room and find bloodstains on the floor. The trio realize that Chanel #2 must have been murdered by The Red Devil. They are confused when they find out that Chanel #2 has been posting photos to her Instagram account. Grace, Zayday, and Denise decide to get some answers from Chanel #2's parents. They find out that Chanel #2 used to date Chad Radwell, Chanel's promiscuous ex-boyfriend.
Denise comes to a conclusion that there has got to be more than one killer. Denise accuses Zayday of being one of The Red Devils, because of her hatred of KKT's bad morals. Grace accuses Chad of being one of the killers because of his morbid obsession with death and his slight necrophilia.
Meanwhile, The Red Devil wields a new weapon on the campus of Wallace University; a chainsaw. Professor Wes Gardner recently taught a film analysis class on "The Texas Chainsaw Massacre,' a horror movie based on true events. The Red Devil begins targeting the Dicky Dollar Scholars. Two Red Devils murder multiple Scholars.
Dean Cathy Munsch and Gigi Caldwell decide to move into the Kappa House due to the severe increase in murders on campus. The problem seems to be escalating and they are determined to figure out who the killers are. Gigi gets annoyed of the dean and decides to sleep on the first floor of the Kappa House. The Red Devil finds Gigi and tries to attack her. Wes comes to her rescue and The Red Devil runs away. The dean leaves her room after hearing Gigi's screams and is accused of being the killer by Gigi and Wes.
"Scream Queens' stars Emma Roberts as Chanel Oberlin, Skyler Samuels as Grace Gardner, Lea Michele as Hester "Neckbrace" Ulrich, Glen Powell as Chad Radwell, Diego Boneta as Pete MartÃnez, Abigail Breslin as Chanel #5, Keke Palmer as Zayday Williams, Nasim Pedrad as Gigi Caldwell, Lucien Laviscount as Earl Grey, Oliver Hudson as Weston "Wes" Gardner, Billie Lourd as Chanel #3, Jamie Lee Curtis as Cathy Munsch, Ariana Grande as Chanel #2, Nick Jonas as Boone, Niecy Nash as Denise Hemphill, Jan Hoag as Ms. Bean, Breezy Eslin as Jennifer, Jeanna Han as Sam, Chelsea Ricketts as Amy, Anna Grace Barlow as Bethany, Grace Phipps as Mandy, McKaley Miller as Sophia, Whitney Meyer as Tiffany, Brianne Howey as Melanie Dorcas; Chanel's KKT presidential predecessor, Deneen Tyler as Shondell; Denise's friend and security guard, Evan Paley as Caufield, Austin Rhodes as Dodger, Aaron Rhodes as Roger, Jim Klock as Detective Chisolm, Tavi Gevinson as Feather, Charisma Carpenter as Mrs. Herfmann, Roger Bart as Dr. Herfmann, Jennifer Aspen as Mandy, Philip Casnoff as Cathy's husband, Patrick Schwarzenegger as Thad Radwell, Chad Michael Murray as Brad Radwell, Julia Duffy as Mrs. Radwell, Alan Thicke as Mr. Radwell.
Ep. 3 "Chainsaw" was written and directed by Ian Brennan. Ep. 4 "Haunted House" airs on Oct. 6. The show's creators are Ryan Murphy, Brad Falchuk, and Ian Brennan. The executive producers are Alexis Martin Woodall, Ian Brennan, Brad Falchuk, and Dante Li Loreto. Robert M. Williams Jr. produced the show. "Scream Queens' is edited by Adam Penn and John Petaja. Its production companies are 20th Century Fox Television, Prospect Films, Ryan Murphy Productions, and Brad Falchuk Teley-vision.